您好，欢迎访问安徽省农业科学院 机构知识库！

Identification of Polymorphism in HTT Gene and its Association with Production Performances in Anhui Local Chicken Breeds

文献类型： 外文期刊

作者： Guo, Pan-pan 1 ; Liu, Wei 2 ; Li, Yan 2 ; Ma, Rui-yu 2 ; Zaigui, Wang 1 ; Zhan, Kai 2 ; Li, Jun-ying 2 ; Liu, Sheng-nan 2 ;

作者机构： 1.Anhui Agr Univ, Coll Life Sci, Hefei, Anhui, Peoples R China

2.Anhui Acad Agr Sci, Inst Anim Husb & Vet Med, Hefei 230031, Anhui, Peoples R China

期刊名称：PAKISTAN JOURNAL OF ZOOLOGY （ 影响因子：0.831； 五年影响因子：0.768 ）

ISSN： 0030-9923

年卷期： 2017 年 49 卷 1 期

页码：

收录情况： SCI

摘要： The aims of this study were to identify genetic polymorphisms of the huntingtin (HTT) gene and to further investigate its association with production performances in two Anhui local chicken breeds A total of 800 chickens (400 Huangshan black chickens and 400 Huainan partridge chickens) of similar age and weight were evaluated in the present study. We extracted DNA from blood samples and analyzed polymorphisms of HTT gene as wells as possible association with egg production performances including age at first egg (AFE), laying rate (LR), egg production (EP), egg weight (EW), average egg weight (AEW) Two polymorphisms (G5083 1C and G62976A) were detected and located in exon 42 and intron 54 in HTT gene, respectively One of them (g 50831 G>C) was a missense mutation. Genotype and allele frequency analysis showed that SNP G62976A and SNP G5083 IC of the HTT gene in chicken had some effects on reproduction traits, and the genotype GG was the advantageous genotype. Additionally, four HIT haplotypes (HI: GG; H2: GC, H3: AG; H4. AC) and their frequency distributions were estimated using the phase program Haplotypes combinations constructed on these two SNPs of HTT gene were associated with some reproduction traits. In particular, diplotype H1H1 had positive effect on reproduction traits, diplotype H2H4 had negative effect of reproduction traits. In conclusion, our study showed that polymorphisms of the HTT gene were significantly associated with egg production traits in two Anhui local chicken breeds, but the suggestions that HTT may be considered as a potential molecular marker for the selection of production performance-related phenotypes in local chicken breeds need to be further verified.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：安徽省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台