您好，欢迎访问安徽省农业科学院 机构知识库！

Two Novel SNPs in RET Gene Are Associated with Cattle Body Measurement Traits

文献类型： 外文期刊

作者： Gao, Yuan 1 ; Huang, Bizhi 2 ; Bai, Fuxia 1 ; Wu, Fei 1 ; Zhou, Zihui 1 ; Lai, Zhenyu 1 ; Li, Shipeng 1 ; Qu, Kaixing 2 ; Ji 1 ;

作者机构： 1.Northwest A&F Univ, Key Lab Anim Genet Breeding & Reprod Shaanxi Prov, Coll Anim Sci & Technol, Xianyang 712100, Shaanxi, Peoples R China

2.Yunnan Acad Grassland & Anim Sci, Kunming 650212, Yunnan, Peoples R China

3.Anhui Acad Agr Sci, Inst Anim Sci & Vet Med, Hefei 230001, Anhui, Peoples R China

关键词： RET gene; SNP; body measurement trait; cattle

期刊名称：ANIMALS （ 影响因子：2.752； 五年影响因子：2.942 ）

ISSN： 2076-2615

年卷期： 2019 年 9 卷 10 期

页码：

收录情况： SCI

摘要： Simple Summary The aim of this study was to identify crucial genes and markers potentially associated with cattle economic traits which would provide a basis for molecular marker-assisted breeding and assist in the genetic selection of cattle. The RET gene plays an important role in the development of the gastrointestinal nervous system, which may influence animal body measurement by nutrient absorption. However, there have been no reports on the effects of the RET gene on the body measurement traits of cattle. Two novel SNPs (c.1407A>G and c.1425C>G) were identified in this study, which were significantly associated with the body measurement of two Chinese cattle breeds (Qinchuan and Nanyang cattle). The results suggest that c.1407A>G and c.1425C>G can be used in cattle growth-related traits marker-assisted selection breeding. Abstract The rearrangement of the transfection (RET) gene, which mediates the functions of the ganglion in the gastrointestinal tract, plays an important role in the development of the gastrointestinal nervous system. Therefore, the RET gene is a potential factor influencing animal body measurement. The aim of this study was to reveal the significant genetic variations in the bovine RET gene and investigate the relationship between genotypes and body measurement in two Chinese cattle breeds (Qinchuan and Nanyang cattle). In this study, two SNPs (c.1407A>G and c.1425C>G) were detected in the exon 7 of RET gene by sequencing. For the SNP1 and SNP2, the GG genotype was significantly associated with body height, hip height, and chest circumference in Qinchuan cattle (p < 0.05). Individuals with an AG-CC genotype showed the lowest value of all body measurement in both breeds. Our results demonstrate that the polymorphisms in the bovine RET gene were significantly associated with body measurement, which could be used as DNA marker on the marker-assisted selection (MAS) and improve the performance of beef cattle.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：安徽省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台