您好，欢迎访问安徽省农业科学院 机构知识库！

Immunogenicity of novel sulfadimethoxide conjugates

文献类型： 外文期刊

作者： Chen, Lei 2 ; Su, Jianyu 1 ; Zhang, Xiangzhai 3 ; Li, Lin 1 ; He, Xiaowei 1 ;

作者机构： 1.S China Univ Technol, Sch Light Ind & Food Sci, Guangzhou 510640, Guangdong, Peoples R China

2.Anhui Acad Agr Sci, Inst Agroprod Proc, Hefei 230031, Peoples R China

3.Hebei Normal Univ Sci & Technol, Key Lab Hebei Prov Prevent Vet Med, Qinhuangdao 066004, Peoples R China

关键词： Sulfadimethoxine (SDM);sulfasulfonamides (SN);sulfadiazine (SD);sulfamethazine (SM2);sulfamethoxypyrazine (SMP);sulfalene (SMZ);sulfaquinoxaline (SQX);rabbit anti-SDM antibodies;soy 11S globulin;SDM-beta-amylase

期刊名称：AFRICAN JOURNAL OF BIOTECHNOLOGY （ 影响因子：0.573； 五年影响因子：0.794 ）

ISSN： 1684-5315

年卷期： 2011 年 10 卷 48 期

页码：

收录情况： SCI

摘要： Sulfadimethoxine (SDM) is an antibiotic commonly added to animal feeds. Anti-SDM antibodies are useful for the detection of residual SDM in foods, feeds and biological fluids by ELISA. In this study, we show that SDM is immunogenic in rabbits when it is conjugated with soy 11S globulin or with beta-amylase. Rabbit anti-SDM antibodies obtained by immunization with SDM-11S and SDM-beta-amylase displayed low cross-reactivity against other sulfonamides, including sulfamethazine (SM2), sulfasulfonamides (SN), sulfadiazine (SD), sulfamethoxypyrazine (SMP), sulfalene (SMZ), sulfaquinoxaline (SQX). Thus, soy 11S globulin and beta-amylase are suitable carriers for the induction of anti-SDM antibodies and have the advantage of being cheaper that BSA.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：安徽省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台