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Resistance integrons: class 1, 2 and 3 integrons

文献类型： 外文期刊

作者： Deng, Yang 1 ; Bao, Xuerui 1 ; Ji, Lili 1 ; Chen, Lei 2 ; Liu, Junyan 1 ; Miao, Jian 1 ; Chen, Dingqiang 3 ; Bian, Huawei 4 ;

作者机构： 1.S China Univ Technol, Coll Light Ind & Food Sci, Guangzhou 510640, Guangdong, Peoples R China

2.Anhui Acad Agr Sci, Inst Agroprod Proc, Hefei 230031, Peoples R China

3.Guangzhou Med Univ, Affiliated Hosp 1, Dept Lab Med, Guangzhou 510120, Peoples R China

4.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510630, Guangdong, Peoples R China

5.Guangzhou Women & Childrens Med Ctr, Guangzhou 510620, Guangdong, Peoples R China

6.Jinan Univ, Affiliated Hosp 1, Guangzhou 510620, Guangdong, Peoples R China

关键词： Antimicrobial resistance;Mobile genetic elements;Horizontal transfer;Resistance integrons

期刊名称：ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS （ 影响因子：3.944； 五年影响因子：4.266 ）

ISSN： 1476-0711

年卷期： 2015 年 14 卷

页码：

收录情况： SCI

摘要： As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and reported to widely spread and extended to a large variety of microorganisms. In China, as one of the currently worst areas for antibiotics abuse, the annual prescription of antibiotics, including both clinical and veterinary treatment, has approaching 140 gram per person and been roughly estimated to be 10 times higher than that in the United Kingdom, which is considered to be a potential area for the emergence of "Super Bugs". Based on the integrons surveillance in Guangzhou, China in the past decade, this review thus aimed at summarizing the role of integrons in the perspective of both clinical setting and environment, with the focus on the occurrence and prevalence of class 1, 2 and 3 integrons.

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