文献类型： 外文期刊

作者： Shi, Yun-Lian ¹ ; Nie, Xu-Liang ² ; Huang, Tao ² ; Shi, Ming-Zhu ² ; Peng, Da-Yong ² ; Ren, Xue-Xiang ³ ; Shi, Xu-Gen; ¹ ;

作者机构： 1.Jiangxi Agr Univ, Coll Agron, Nanchang 330045, Jiangxi, Peoples R China

2.Jiangxi Agr Univ, Coll Sci, Nanchang 330045, Jiangxi, Peoples R China

3.Anhui Acad Agr Sci, Inst Plant Protect & Agroprod Safety, Hefei 230001, Peoples R China

4.Jiangxi Agr Univ, Coll Land Resources & Environm, Nanchang 330045, Jiangxi, Peoples R China

关键词： 2-(N-tert-butoxycarbonylamino) pyridine derivatives; Synthesis; Crystal structure; Inhibitory activities

期刊名称：JOURNAL OF CHEMICAL CRYSTALLOGRAPHY （ 影响因子：0.603； 五年影响因子：0.51 ）

ISSN： 1074-1542

年卷期：

页码：

收录情况： SCI

摘要： 2-(N-tert-butoxycarbonylamino) pyridine and 2-(N-tert-butoxycarbonylamino)-3-methylpyridine were synthesized in a one-step method using either 2-aminopyridine or 2-amino-3-methyphyridine with tert-butylcarbonyl anhydride as the starting materials. The products were characterized by single-crystal X-ray diffraction, H-1 NMR, C-13 NMR, and HRMS. The biological activity of the two compounds against five fungi was determined. 2-(N-tert-butoxycarbonylamino) pyridine has more than 50% inhibitory activity against Pyricularia oryzae, Colletotrichum gloeosporioides, and Alternaria alternate. In addition, the inhibitory activity of 2-(N-tert-butoxycarbonylamino)-3-methylpyridine against Alternaria alternate reached 67.69%. Graphic Two 2-BOC aminopyridine derivatives were synthesized and structurally characterized by H-1 NMR, C-13 NMR, HRMS analysis and X-ray crystal diffraction. The inhibitory activity both compounds was studied. [GRAPHICS] .