文献类型： 外文期刊
作者： Wang, Huakai 1 ; Ma, Yongxi 1 ; Iacone, Roberto 1 ;
作者机构： 1.China Agr Univ, Coll Anim Sci & Technol, Dept Anim Nutr & Feed Sci, State Key Lab Anim Nutr, Beijing 100193, Peoples R China
2.Anhui Acad Agr Sci, Inst Anim Husb & Vet Med, Nongkenan Rd 40, Hefei 230031, Peoples R China
关键词： bioavailability; bone health; dietary intake; dietary source; vitamin K; vitamin K-dependent protein
期刊名称：NUTRIENTS （ 影响因子：5.9； 五年影响因子：6.6 ）
ISSN：
年卷期： 2023 年 15 卷 23 期
页码：
收录情况： SCI
摘要： Vitamin K (VK), a fat-soluble vitamin, is essential for the clotting of blood because of its role in the production of clotting factors in the liver. Moreover, researchers continue to explore the role of VK as an emerging novel bioactive molecule with the potential function of improving bone health. This review focuses on the effects of VK on bone health and related mechanisms, covering VK research history, homologous analogs, dietary sources, bioavailability, recommended intake, and deficiency. The information summarized here could contribute to the basic and clinical research on VK as a natural dietary additive and drug candidate for bone health. Future research is needed to extend the dietary VK database and explore the pharmacological safety of VK and factors affecting VK bioavailability to provide more support for the bone health benefits of VK through more clinical trials.
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