Genome-Wide Association Study Reveals Growth-Related SNPs and Candidate Genes in Largemouth Bass (Micropterus salmoides) Adapted to Hypertonic Environments
文献类型： 外文期刊
作者： Ding, Miaomiao 1 ; Tao, Yifan 2 ; Hua, Jixiang 1 ; Dong, Yalun 2 ; Lu, Siqi 2 ; Qiang, Jun 1 ; He, Jixiang 3 ;
作者机构： 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi 214081, Peoples R China
2.Chinese Acad Fishery Sci, Minist Agr & Rural Affairs, Freshwater Fisheries Res Ctr, Key Lab Freshwater Fisheries & Germplasm Resources, Wuxi 214081, Peoples R China
3.Anhui Acad Agr Sci, Fisheries Res Inst, Hefei 230041, Peoples R China
关键词：
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：4.9； 五年影响因子：5.7 ）
ISSN： 1661-6596
年卷期： 2025 年 26 卷 5 期
页码：
收录情况： SCI
摘要： Sustainable development of the largemouth bass industry is hindered by limited freshwater resources. Consequently, the expansion of farming space by brackish and saline water aquaculture has become imperative. Largemouth bass is an economically important freshwater fish species. However, there is presently a lack of germplasm resources with the capacity to adapt to hypertonic environments and maintain rapid growth. A genome-wide association study is a technique used for the detection of genetic variants associated with specific phenotypic traits. In this study, we firstly applied this technique to explore the potential single-nucleotide polymorphism (SNP) locus and candidate genes associated with rapid growth and adaptation to the hypertonic environment of largemouth bass. A total of 10 potential growth-related SNPs were obtained on chromosome 16, and SNP16:4120214 was a significant SNP peak. Based on these SNPs, 23 candidate genes were annotated in the genome, including Nkcc1, Mapkap1, Hmgcs1, Slc27a6, and Shroom3. Shroom3 expression was significantly higher in individuals enriched for the most growth-advantageous genotypes. Shroom3 upregulation is beneficial for fish growth in hyperosmotic environments. This study provides insight into the genetic basis of rapid growth in hypertonic environments and foundational information for the future breeding of salt-tolerant largemouth bass.
- 相关文献
作者其他论文 更多>>
-
Disease resistance and genetic characteristics of genetically selected largemouth bass (Micropterus salmoides) revealed by whole genome resequencing
作者：Sun, Hui;Hua, Jixiang;Tao, Yifan;He, Jie;Qiang, Jun;Tao, Yifan;He, Jie;Wang, Qingchun;Dong, Yalun;Qiang, Jun;He, Jixiang
关键词：Micropterus salmoides; LMBV; Whole genome resequencing; Genetic variation; Artificial selection
-
PcASTA in Procambarus clarkii, a novel astaxanthin gene affecting shell color
作者：Chen, Xiajun;Chen, Jing;Huang, Long;Wu, Benli;Wu, Cangcang;He, Jixiang;Bai, Zhiyi
关键词：Procambarus clarkii; carotenoid; astaxanthin; shell; color
-
Comparative Analysis of the Growth, Physiological Responses, and Gene Expression of Chinese Soft-Shelled Turtles Cultured in Different Modes
作者：Wu, Benli;Huang, Long;Wu, Cangcang;Chen, Jing;Chen, Xiajun;He, Jixiang
关键词：rice-turtle co-culture; pond culture; growth performance; physiological response; gene expression
-
Adaptation and feeding preference of Chinese soft-shelled turtle ( Pelodiscus sinensis) ) to different feeding levels in rice-turtle - turtle co-culture system
作者：Wu, Benli;Wu, Cangcang;Huang, Long;Chen, Jing;Chen, Xiajun;He, Jixiang
关键词：Feeding level; Rice-turtle co-culture; Growth performance; Behavioral and physiological responses; Gene expression
-
Effects of Functional Oligosaccharides Extracted from Straw on the Growth, Feeding, Physiology, Histology, Muscle Texture, and Gut Microbiota of Micropterus salmoides
作者：Wu, Benli;Huang, Long;Wu, Cangcang;Chen, Jing;Chen, Xiajun;Wang, Xiang;Cui, Kai;He, Jixiang;Liu, Zhigang
关键词：
-
Identification of a coproporphyrinogen-III oxidase gene and its correlation with nacre color in Hyriopsis cumingii
作者：Chen, Xiajun;He, Jixiang;Chen, Xiajun;Zhang, Mengying;Bai, Zhiyi;Li, Jiale;Chen, Xiajun;Zhang, Mengying;Bai, Zhiyi;Li, Jiale;Bai, Zhiyi;Li, Jiale
关键词：
-
Effects of feeding frequency on growth performance, feed intake, metabolism and expression of fgf21 in grass carp (Ctenopharyngodon idellus)
作者：Wu, Benli;Huang, Long;Chen, Jing;Zhang, Ye;Chen, Xiajun;Wu, Cangcang;He, Jixiang;Deng, Xiaojie;Gao, Jing
关键词：Grass carp; Feeding frequency; Ingestion; Metabolism; fgf21 gene expression
